Nucleofill Strong is the highest-strength polynucleotide skin booster within the updated Nucleofill range. It is formulated for patients presenting with advanced skin ageing, marked laxity and reduced dermal density. The original Nucleofill portfolio consisted of Nucleofill 20, Nucleofill 25 and Nucleofill Eyes. As part of the indication-led restructuring: Nucleofill 20 became Medium Nucleofill Eyes became Soft Plus Nucleofill 25 was divided into Medium Plus and Strong Strong Plus represents the higher-concentration option within the former 25 category. This separation allows practitioners to distinguish between moderate ageing concerns and more advanced laxity or body indications. In clinical practice, Nucleofill Strong Plus is typically selected for: Advanced facial ageing Marked skin laxity Reduced dermal thickness Mature skin requiring higher PN concentration Body areas such as abdomen, inner arms and thighs where appropriate It is positioned as a regenerative skin quality treatment rather than a volumising product and is suited to thicker tissue and more significant structural decline. How It Works Nucleofill Strong contains polymerised polynucleotides at the highest concentration within the range. Polynucleotides are hydrophilic molecules that bind water within the extracellular matrix, contributing to tissue hydration. They also support an environment favourable to fibroblast activity and normal collagen and elastin production processes. The formulation is designed to: Support dermal structure Contribute to improved elasticity Assist with hydration in compromised tissue Support overall skin quality in advanced cases The approach remains regenerative and supportive rather than volumising. Key Benefits Highest-density PN formulation in the Nucleofill range Designed for advanced laxity and mature skin Suitable for selected facial and body areas Non-volumising regenerative protocol Clear clinical differentiation from Medium Plus
